PhD positions in the EU Horizon 2020 Marie Skłodowska-Curie Project RENOIR:

REcreating the ideal Niche: environmental control Of cell Identity in Regenerating and diseased muscles

RENOIR will recruit 13 Early Stage Researchers (ESRs) who will be all enrolled in PhD programmes.
The successful training of the ESRs will be achieved by complementing cutting-edge science via joint research projects in both academic and non-academic setting, with local and network training in science valorisation, responsible research and other transferable skills. Furthermore, as a complement to the industry placement, there is a strong emphasis on providing training in innovation-related and soft skills such as IP management and entrepreneurship.

Secondments to other laboratories within RENOIR are a mandatory part of the training activities. Each ESR will at least have 2 secondments lasting 1-4 months, and they will have the opportunity to follow local training in the host laboratory and will enrich their expertise and potential, as well as their interactive and collaborative skills.

The 13 ESRs projects are distinct but complementary and all synergize to achieve RENOIR specific research objectives, which are:

  1. To identify the distinctive molecular fingerprint of the different cell components of the muscle regenerating niche.
  2. To define the pattern of the cellular interactions and the influence of the niche environment on muscle homeostasis, regeneration and aging.
  3. To combine the use of advanced biomaterials and biopharma to optimize ex vivo modelling of the niche and to achieve in vivo delivery of compounds for efficient tissue maintenance and regeneration.

ESR Projects

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ESR1

Study of the molecular mechanism of Endothelial to Mesenchymal Transition during muscle regeneration and crosstalk with the immune system in vivo and in vitro

PHD PROJECT DESCRIPTION
IGB CNR

ESR2

Extrinsic control of skeletal muscle remodelling: molecular mechanisms and therapeutic implications

PHD PROJECT DESCRIPTION
Lyon 1

ESR3

Role of macrophages in degenerative myopathies and fibrosis

PHD PROJECT DESCRIPTION
Pompeu Fabra University

ESR4

Fibrogenic progenitors in skeletal muscle

PHD PROJECT DESCRIPTION
University of Manchester

ESR5

Lineage tracing of PCs in developing and dystrophic muscle

PHD PROJECT DESCRIPTION
University of Debrecen

ESR6

Epigenomics of macrophage phenotypes and the contribution of transcription processes contributing to phenotype switch

PHD PROJECT DESCRIPTION
Fondazione Santa Lucia

ESR7

Dynamic changes in transcription and epigenetic profile of fibro-adipogenic progenitors in healthy and dystrophic muscles, and modulation by epigenetic drugs

PHD PROJECT DESCRIPTION
University of Naples

ESR8

Controlling cell microenvironment: engineering artificial niches to study muscle degeneration-regeneration in vitro

PHD PROJECT DESCRIPTION
King’s College London

ESR9

Cellular and molecular signature of cardioPICs

PHD PROJECT DESCRIPTION
Eden Microfluidics

ESR10

Microfluidic bioreactor for high control over fluid and reagent delivery

PHD PROJECT DESCRIPTION
Technion Israel Institute of Technology

ESR11

Novel Bioengineering approaches for studying muscle tissue homeostasis and regeneration

PHD PROJECT DESCRIPTION

ESR12

Use of a non-oxidizable form of HMGB1 for muscle repair therapies

PHD PROJECT DESCRIPTION
Cherry Biotech

ESR13

Live observation of Endothelial to Mesenchymal Transition

PHD PROJECT DESCRIPTION
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